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A mod answered and I answered the guy in a normal way, but they deleted my reply and blocked my account. As here reported, these observations are mainly based on self-reporting of the symptomatology by the patients and few clinical studies have been performed so far. For what it's worth, here's a couple similar success stories involving numbness, but from PSSD instead of PFS: Testosterone along with initial estrogen management , completely cured my pssd, everything from numbness, to hard on quality , no morning wood, to actually having sexual desires again. A community dedicated to people suffering long term effects after taking 5-ar inhibitors such as Propecia/Finasteride, or for people who wish to know more about the constellation of symptoms commonly known as Post Finasteride Syndrome. Therefore, I cut the pills in half (2.5mg) and toss the other half. I has numbness also. And posted the article and some cliffs about his solution. I have had a recent report of a man who went on Human Growth Hormone and reversed his post finasteride syndrome sexual dysfunction. Unauthorized use of these marks is strictly prohibited. I took a large amount of DHT (proviron) for 7 weeks at 200 mg per day to reduce receptor sensitivity to DHT. Biomolecules. Althof HE, et al. Liu L, Zhao S, Li F, Li E, Kang R, Luo L, Luo J, Wan S, Zhao Z. J Sex Med. What's the best treatment to use to try to get my partner pregnant? https://forum.propeciahelp.com/t/joekool-s-story-long-term-hcg/46717. Their attitude is 100% there is no cure, it wont get better, nothing works, anything that does work doesnt work long term, and thats just how it is. Do a physical exam, which will likely include an exam of your penis, testicles and rectum. Will my partner and I likely need to use assisted reproductive technology, such as intrauterine insemination, to achieve pregnancy? reading time: 43 official website and that any information you provide is encrypted Contemporary management of disorders of male orgasm and ejaculation. Your doctor will ask you to empty your bladder, masturbate to climax and then provide a urine sample for laboratory analysis. Write down key personal information, including prior surgeries or pelvic radiation, any major stresses, or recent life changes. A single copy of these materials may be reprinted for noncommercial personal use only. FOIA AR: androgen receptor; CSF: cerebrospinal fluid; MRI: magnetic resonance imaging; SRD5A2: 5 alpha reductase type 2 gene. Fertility and Sterility. Next to no sensitivity in my genitals. After numerous labs, I have determined that a dose of 2-3 mg is optimal for keeping my DHT within the normal range. | How To Diagnose And Reverse It. I need to get back over there and check it out I guess. ._3-SW6hQX6gXK9G4FM74obr{display:inline-block;vertical-align:text-bottom;width:16px;height:16px;font-size:16px;line-height:16px} "I had a case of PFS that was a severe as it gets. (photo). Hum. I did this for 6 months straight but at the 10th week or so, the improvements were weekly. They have some pretty smart people and are open to trying about anything, and isnt as negative as the other forum. Can electrical brain stimulation boost attention, memory, and more? Melcangi RC, Caruso D, Abbiati F, Giatti S, Calabrese D, Piazza F, Cavaletti G. J Sex Med. Drugs generally won't help if retrograde ejaculation is due to surgery that causes permanent physical changes of your anatomy. Just bombarding their bodies with strong androgens. Your doctor might also ask about any health problems, surgeries or cancers you've had and what medications you take. For details, see text. The problem is that most docs prescribe it at excessively high levels (5 mg/day). I'll be interested to see if this has any effects on my weight loss endeavors. Around 8 months and i was pretty much recovered. AR: androgen receptor; DHP: dihydroprogesterone; DHT: dihydrotestosterone; ER: estrogen receptor beta; PR: progesterone receptor; PROG: progesterone; T: testosterone; THP: tetrahydroprogesterone. Diagnosing and Reversing It", Is Post Finasteride Syndrome Real? Over time, several studies have demonstrated that finasteride is a safe and well-tolerated drug, with rare and reversible side effects such as reduced sexual libido and ejaculatory volume, most commonly observed when prescribed in post-finasteride syndrome Sometimes, more-advanced assisted reproductive techniques are needed. Post Finasteride Syndrome Real? Diagnosing That is 250IU, not a typo so youll mix your 5000iu HCG with 5CC water and take 1/4 CC intramuscular three times a week using an insulin needle Have you heard about it? 2015 Sep;16(3):177-98. doi: 10.1007/s11154-015-9319-y. I recovered and I hope all of you suffering from PFS recover too. Mehta A, et al. They kept saying it was on the verge of having a major announcement 2 YEARS ago. https://www.isarms.com/forums/threads/post-finasteride-syndrome.18175/. Finasteride oral tablet Many men with retrograde ejaculation are able to get their partners pregnant once they seek treatment. Not orgasm strength and sperm levels have returned, just waiting on my brain to communicate with my penis when its time for sexual intercourse. My personal experience is that finasteride is an important medication for older guys on TRT that are experiencing BPH. I also tried testosterone treatment but it had almost no effect regardless of dosage. In some people with PFS, DHT might be normal, but testosterone and cortisol low and estrogen and prolactin high. eCollection 2021 Oct. See this image and copyright information in PMC. This can be caused by damage to the prostate or semen-producing glands as a result of surgery or radiation treatment for cancer in the pelvic area. All rights reserved. Im only able to maintain arousal under very peculiar circumstances, and even thats not the level of hardness Im used to having pre-fin. The site is secure. This content does not have an Arabic version. Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron. I was on TRT when I got PFS. WebPost-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested in clinical symptoms that develop and persist in patients during and/or after discontinuing finasteride treatment in men with pattern hair loss (androgenetic alopecia) or Pharmaceuticals (Basel). This is not proof that finasteride is to blame, since a variety of medical conditions and other prescription drugs could explain the sexual symptoms. Make a donation. I'm not a gym rat, I just make sure to walk 3-5 miles a day and do my best to watch what I eat (that's always been the case.) (Read up on desensitization of Leydig Cells but don't get nervous at this plan) Ferri FF. However, the side effects of a medication usually go away when you stop taking it. sharing sensitive information, make sure youre on a federal https://forum.propeciahelp.com/t/my-story-yes-it-was-messy-and-yes-i-am-fine-now/5456. At higher doses, finasteride (Proscar) can also treat benign prostatic hyperplasia (BPH). That fog, that mental barrier that kept me feeling a distance from myself had totally lifted. In: Campbell-Walsh-Wein Urology. Can sperm be retrieved from my bladder and used for fertility treatment? It is available as a generic. -, Baig M.S., Kolasa-Wolosiuk A., Pilutin A., Safranow K., Baranowska-Bosiacka I., Kabat-Koperska J., Wiszniewska B. Finasteride-induced inhibition of 5alpha-reductase type 2 could lead to kidney damage-animal, experimental study. Post-Finasteride Syndrome: Current Views and Where do we Stand? How much worse can it get then being a lifeless piece of flesh that hasnt been erect or had any kind of sensation in months and months? After stopping 7 weeks later (when I ran out of my proviron), things felt off for a few weeks but then after around two months I got back to my pre-PFS state. Of course there are some people with severe pfs but even then just wait is shit advice. Personally, I believe its become the boogeyman for a bucket list of sexual problems. Before Best, Dr. Emer. The steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting. reddit Keywords: Samplaski MK, et al. https://forum.propeciahelp.com/t/i-think-im-healed-after-six-year-nightmare/35477. .ehsOqYO6dxn_Pf9Dzwu37{margin-top:0;overflow:visible}._2pFdCpgBihIaYh9DSMWBIu{height:24px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu{border-radius:2px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:focus,._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:hover{background-color:var(--newRedditTheme-navIconFaded10);outline:none}._38GxRFSqSC-Z2VLi5Xzkjy{color:var(--newCommunityTheme-actionIcon)}._2DO72U0b_6CUw3msKGrnnT{border-top:none;color:var(--newCommunityTheme-metaText);cursor:pointer;padding:8px 16px 8px 8px;text-transform:none}._2DO72U0b_6CUw3msKGrnnT:hover{background-color:#0079d3;border:none;color:var(--newCommunityTheme-body);fill:var(--newCommunityTheme-body)} Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. Serious Side Effects: Post Finasteride Syndrome In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). 8600 Rockville Pike What was the article? In such cases, treatment depends on the underlying cause. Careers. Don't listen to bad doctors who tell you its all in your head. I cannot say enough about this. I am not aware or scientific evidence that back this up at this time. I will tell you how I solved my problem with post-finasteride syndrome, which produces no erections or little libido even if you have stopped taking the famous drug years ago. .s5ap8yh1b4ZfwxvHizW3f{color:var(--newCommunityTheme-metaText);padding-top:5px}.s5ap8yh1b4ZfwxvHizW3f._19JhaP1slDQqu2XgT3vVS0{color:#ea0027} What websites do you recommend visiting? Elsevier; 2021. https://www.clinicalkey.com. Therefore, understand that I can't promise this will work for youbut for me? Epub 2016 Jul 27. I took a step back and said forget about PFS with these blood tests and these symptoms, whats the normal course of action? No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Finally Cured From Post Finasteride Syndrome I did a cycle of hcg 250ui m/w/f for 6 months + a week and a half of clomid 25 everyday + DHEA (I know I'm a idiot) More or less cured me from no low libido and all that great stuff for over a year now and I'm off everything. Lol, now they banned me, just look at the reason: Dismissive of survey in first few posts; insistently advocated for dangerous and misleading article on PFS. Jefferys A, et al. Why not save the other half for your next dose? Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: Imipramine, an antidepressant. https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal-optimization/. The article stated proviron was the best potential cure in his opinion. I dont really understand why theyre like that. and transmitted securely. Accessed Sept. 15, 2016. Mods are always talking about the survey too, I said a survey wont cure us and we could be be waiting for 10 years if we dont do anything. ._38lwnrIpIyqxDfAF1iwhcV{background-color:var(--newCommunityTheme-widgetColors-lineColor);border:none;height:1px;margin:16px 0}._37coyt0h8ryIQubA7RHmUc{margin-top:12px;padding-top:12px}._2XJvPvYIEYtcS4ORsDXwa3,._2Vkdik1Q8k0lBEhhA_lRKE,.icon._2Vkdik1Q8k0lBEhhA_lRKE{border-radius:100%;box-sizing:border-box;-ms-flex:none;flex:none;margin-right:8px}._2Vkdik1Q8k0lBEhhA_lRKE,.icon._2Vkdik1Q8k0lBEhhA_lRKE{background-position:50%;background-repeat:no-repeat;background-size:100%;height:54px;width:54px;font-size:54px;line-height:54px}._2Vkdik1Q8k0lBEhhA_lRKE._1uo2TG25LvAJS3bl-u72J4,.icon._2Vkdik1Q8k0lBEhhA_lRKE._1uo2TG25LvAJS3bl-u72J4{filter:blur()}.eGjjbHtkgFc-SYka3LM3M,.icon.eGjjbHtkgFc-SYka3LM3M{border-radius:100%;box-sizing:border-box;-ms-flex:none;flex:none;margin-right:8px;background-position:50%;background-repeat:no-repeat;background-size:100%;height:36px;width:36px}.eGjjbHtkgFc-SYka3LM3M._1uo2TG25LvAJS3bl-u72J4,.icon.eGjjbHtkgFc-SYka3LM3M._1uo2TG25LvAJS3bl-u72J4{filter:blur()}._3nzVPnRRnrls4DOXO_I0fn{margin:auto 0 auto auto;padding-top:10px;vertical-align:middle}._3nzVPnRRnrls4DOXO_I0fn ._1LAmcxBaaqShJsi8RNT-Vp i{color:unset}._2bWoGvMqVhMWwhp4Pgt4LP{margin:16px 0;font-size:12px;font-weight:400;line-height:16px}.icon.tWeTbHFf02PguTEonwJD0{margin-right:4px;vertical-align:top}._2AbGMsrZJPHrLm9e-oyW1E{width:180px;text-align:center}.icon._1cB7-TWJtfCxXAqqeyVb2q{cursor:pointer;margin-left:6px;height:14px;fill:#dadada;font-size:12px;vertical-align:middle}.hpxKmfWP2ZiwdKaWpefMn{background-color:var(--newCommunityTheme-active);background-size:cover;background-image:var(--newCommunityTheme-banner-backgroundImage);background-position-y:center;background-position-x:center;background-repeat:no-repeat;border-radius:3px 3px 0 0;height:34px;margin:-12px -12px 10px}._20Kb6TX_CdnePoT8iEsls6{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex;margin-bottom:8px}._20Kb6TX_CdnePoT8iEsls6>*{display:inline-block;vertical-align:middle}.t9oUK2WY0d28lhLAh3N5q{margin-top:-23px}._2KqgQ5WzoQRJqjjoznu22o{display:inline-block;-ms-flex-negative:0;flex-shrink:0;position:relative}._2D7eYuDY6cYGtybECmsxvE{-ms-flex:1 1 auto;flex:1 1 auto;overflow:hidden;text-overflow:ellipsis}._2D7eYuDY6cYGtybECmsxvE:hover{text-decoration:underline}._19bCWnxeTjqzBElWZfIlJb{font-size:16px;font-weight:500;line-height:20px;display:inline-block}._2TC7AdkcuxFIFKRO_VWis8{margin-left:10px;margin-top:30px}._2TC7AdkcuxFIFKRO_VWis8._35WVFxUni5zeFkPk7O4iiB{margin-top:35px}._1LAmcxBaaqShJsi8RNT-Vp{padding:0 2px 0 4px;vertical-align:middle}._2BY2-wxSbNFYqAy98jWyTC{margin-top:10px}._3sGbDVmLJd_8OV8Kfl7dVv{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:21px;margin-top:8px;word-wrap:break-word}._1qiHDKK74j6hUNxM0p9ZIp{margin-top:12px}.Jy6FIGP1NvWbVjQZN7FHA,._326PJFFRv8chYfOlaEYmGt,._1eMniuqQCoYf3kOpyx83Jj,._1cDoUuVvel5B1n5wa3K507{-ms-flex-pack:center;justify-content:center;margin-top:12px;width:100%}._1eMniuqQCoYf3kOpyx83Jj{margin-bottom:8px}._2_w8DCFR-DCxgxlP1SGNq5{margin-right:4px;vertical-align:middle}._1aS-wQ7rpbcxKT0d5kjrbh{border-radius:4px;display:inline-block;padding:4px}._2cn386lOe1A_DTmBUA-qSM{border-top:1px solid var(--newCommunityTheme-widgetColors-lineColor);margin-top:10px}._2Zdkj7cQEO3zSGHGK2XnZv{display:inline-block}.wzFxUZxKK8HkWiEhs0tyE{font-size:12px;font-weight:700;line-height:16px;color:var(--newCommunityTheme-button);cursor:pointer;text-align:left;margin-top:2px}._3R24jLERJTaoRbM_vYd9v0._3R24jLERJTaoRbM_vYd9v0._3R24jLERJTaoRbM_vYd9v0{display:none}.yobE-ux_T1smVDcFMMKFv{font-size:16px;font-weight:500;line-height:20px}._1vPW2g721nsu89X6ojahiX{margin-top:12px}._pTJqhLm_UAXS5SZtLPKd{text-transform:none} Now and for the past six months, I feel great, my libido is great, mental issues are gone, ED is gone. I went from barely able to get an erection to having 4 very pleasurable orgasms on the third day. These hippocampal neurogenesis changes after finasteride treatment have been linked to emotional behavior and this might contribute to the pathophysiology of affective disorders in humans. I also started a thread but they merged it. more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal I do not think we have an answer to that question one way or the other. If a high volume of sperm is found in your urine, you have retrograde ejaculation. 12th ed. I just decided to get back on gear after a year off + dutasteride during that time. The Baylor study STILL hasnt been released? The symptoms of PFS start to subside within four to eight months after discontinuing the medicine. WebHow to Correct Post Finasteride Syndrome Minimize Stressors. This stuff WORKS. Is there a generic alternative to the medicine you're prescribing me? Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight lossfrom exercises to build a stronger core to advice on treating cataracts. But on day 3, I felt like my old self. Federal government websites often end in .gov or .mil. What is infertility? Even Viagra wouldnt get me hard. Incredible! Mild side effects that have been reported with finasteride include: ejaculation problems. If your doctor thinks drugs you are taking might be affecting your ability to ejaculate normally, he or she might have you stop taking them for a period of time. Its like they want to hide possible solutions. WebPost finasteride syndrome is real. Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. I remember being depressed, emasculated, and hopeless. Get the latest in health news delivered to your inbox! Minoxidil is FDA approved for genetic hair loss - it does not help other conditions quite so much. I feel like I have my life back. there are many options including peptides, and HCG as well as clomid/arimidex. PDF | Finasteride was patented in 1984 and approved for medical use in 1992. WebPost-finasteride syndrome occurs in men whove taken finasteride to treat hair loss or enlarged prostates. I did three months on testosterone injections and muscle building. ._1LHxa-yaHJwrPK8kuyv_Y4{width:100%}._1LHxa-yaHJwrPK8kuyv_Y4:hover ._31L3r0EWsU0weoMZvEJcUA{display:none}._1LHxa-yaHJwrPK8kuyv_Y4 ._31L3r0EWsU0weoMZvEJcUA,._1LHxa-yaHJwrPK8kuyv_Y4:hover ._11Zy7Yp4S1ZArNqhUQ0jZW{display:block}._1LHxa-yaHJwrPK8kuyv_Y4 ._11Zy7Yp4S1ZArNqhUQ0jZW{display:none} Yeah the joe_kool guy or whatever his name is had really good luck with TRT, he is honestly the reason I went down this road. Last time I was on there they had started discussing some relationships between HCG and Thyroid? Finally Cured From Post Finasteride Syndrome | Ray Peat In some cases, sperm can be recovered from the bladder, processed in the laboratory and used to inseminate your partner (intrauterine insemination). 2022 Oct 26;12(11):1567. doi: 10.3390/biom12111567. After 4 months of no progress whatsoever I tried the regimen that saved me - at least thats the only explanation I have. Arimidex 0.5mg-3mg a day as needed (keep this dose around 1mg a day, too high and you will have low estrogen, torem may prevent you from needing it, everyone is different, I may not need it anymore, I recommend taking it only as needed, Torem 60mg a day (new drug instead of hcg that is an estrogen blocker and being tested as a treatment for androgen insensitivity), DHEA 50mg 1-2X a day (sometimes 2 X if I feel I need a mood boost), Calcium D Glucarate 1500mg (as many times a day as I remember, about 3X is good), Reservatrol (whatever dose a day, its an extra), https://forum.propeciahelp.com/t/final-protocol-100-pfs-reversal-with-dht-therapy-lastpost/7845/2147. These include: Prostate pain Persistent fatigue, exhaustion Stomach pains and digestive problems Constipation Blurry vision Propecia is the Biggest Regret of my Life Taking Propecia is the biggest regret of my life, PK said. Post-finasteride syndrome: a surmountable challenge for doi: 10.1177/0960327119842195. This area was the most recovery and reversal of symptoms. Bethesda, MD 20894, Web Policies Do you have diabetes or any other chronic health problems? How is your dick being equivalent to your thumb not severe? two months back to life after being dead for six years. With prostate cancer deaths overtaking that of breast cancer, it is important to know the side effects of finasteride. Ejaculation and orgasm disorders. Retrograde ejaculation can be especially challenging if you and your partner want to conceive a child. They claim its more to cover their ass because they dont want people trying whatever unproven solution and get worse and commit suicide or something. Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. Answer: Hormonal optimization while on finesteride there are many options including peptides, and HCG as well as clomid/arimidex. ._9ZuQyDXhFth1qKJF4KNm8{padding:12px 12px 40px}._2iNJX36LR2tMHx_unzEkVM,._1JmnMJclrTwTPpAip5U_Hm{font-size:16px;font-weight:500;line-height:20px;color:var(--newCommunityTheme-bodyText);margin-bottom:40px;padding-top:4px;text-align:left;margin-right:28px}._2iNJX36LR2tMHx_unzEkVM{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex}._2iNJX36LR2tMHx_unzEkVM ._24r4TaTKqNLBGA3VgswFrN{margin-left:6px}._306gA2lxjCHX44ssikUp3O{margin-bottom:32px}._1Omf6afKRpv3RKNCWjIyJ4{font-size:18px;font-weight:500;line-height:22px;border-bottom:2px solid var(--newCommunityTheme-line);color:var(--newCommunityTheme-bodyText);margin-bottom:8px;padding-bottom:8px}._2Ss7VGMX-UPKt9NhFRtgTz{margin-bottom:24px}._3vWu4F9B4X4Yc-Gm86-FMP{border-bottom:1px solid var(--newCommunityTheme-line);margin-bottom:8px;padding-bottom:2px}._3vWu4F9B4X4Yc-Gm86-FMP:last-of-type{border-bottom-width:0}._2qAEe8HGjtHsuKsHqNCa9u{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-bodyText);padding-bottom:8px;padding-top:8px}.c5RWd-O3CYE-XSLdTyjtI{padding:8px 0}._3whORKuQps-WQpSceAyHuF{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px}._1Qk-ka6_CJz1fU3OUfeznu{margin-bottom:8px}._3ds8Wk2l32hr3hLddQshhG{font-weight:500}._1h0r6vtgOzgWtu-GNBO6Yb,._3ds8Wk2l32hr3hLddQshhG{font-size:12px;line-height:16px;color:var(--newCommunityTheme-actionIcon)}._1h0r6vtgOzgWtu-GNBO6Yb{font-weight:400}.horIoLCod23xkzt7MmTpC{font-size:12px;font-weight:400;line-height:16px;color:#ea0027}._33Iw1wpNZ-uhC05tWsB9xi{margin-top:24px}._2M7LQbQxH40ingJ9h9RslL{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px} @keyframes _1tIZttmhLdrIGrB-6VvZcT{0%{opacity:0}to{opacity:1}}._3uK2I0hi3JFTKnMUFHD2Pd,.HQ2VJViRjokXpRbJzPvvc{--infoTextTooltip-overflow-left:0px;font-size:12px;font-weight:500;line-height:16px;padding:3px 9px;position:absolute;border-radius:4px;margin-top:-6px;background:#000;color:#fff;animation:_1tIZttmhLdrIGrB-6VvZcT .5s step-end;z-index:100;white-space:pre-wrap}._3uK2I0hi3JFTKnMUFHD2Pd:after,.HQ2VJViRjokXpRbJzPvvc:after{content:"";position:absolute;top:100%;left:calc(50% - 4px - var(--infoTextTooltip-overflow-left));width:0;height:0;border-top:3px solid #000;border-left:4px solid transparent;border-right:4px solid transparent}._3uK2I0hi3JFTKnMUFHD2Pd{margin-top:6px}._3uK2I0hi3JFTKnMUFHD2Pd:after{border-bottom:3px solid #000;border-top:none;bottom:100%;top:auto}